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Home > E. Pathology by systems > Reproductive system > Male genital system > Testis > spermatogonia


Sunday 4 February 2018



Definition : A spermatogonium (plural: spermatogonia) is an undifferentiated male germ cell. Spermatogonia undergo spermatogenesis to form mature spermatozoa in the seminiferous tubules of the testis.

There are three subtypes of spermatogonia in humans:

- Type A (dark) cells, with dark nuclei. These cells are reserve spermatogonial stem cells which do not usually undergo active mitosis.
- Type A (pale) cells, with pale nuclei. These are the spermatogonial stem cells that undergo active mitosis. These cells divide to produce Type B cells.
- Type B cells, which divide to give rise to primary spermatocytes.