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fetal gut-like gastric adenocarcinoma with “blastoma”-like component
Tuesday 28 March 2017
Fetal gut-like Gastric adenocarcinoma with “blastoma”-like component
Images
https://twitter.com/PathologyTweet/status/846344875020898304
Synopsis
fetal gut-like differentiation, yolk sac-like areas and primitive blastoma foci of tubules embedded in blastema
Glands and tubules strongly expressed SALL4 indicating primitive stem cell differentiation. Focal alpha-fetoprotein immunopositivity
Blastemal stroma was strongly positive for glypican-3 a fetal oncoprotein
Expands the remit of primitive, fetal gastric adenocarcinoma
Paywall references
An unusual primary malignant tumor of the stomach: Fetal gut-like Gastric adenocarcinoma with “blastoma”-like component. 2017. doi : 10.1016/j.humpath.2017.02.023
