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Wednesday 15 March 2017

Panfolliculoma is a benign follicular tumor comprised of all components of the hair follicle. We report three cases of panfolliculoma with a solid, endophytic architecture, which at scanning magnification had the profile of a hair follicle.

The epithelial components included uniform dark blue germinative cells, matrical cells, clear cells and cells containing trichohyaline granules.

All the cases also had a central hyperkeratotic horn resembling a hair shaft.

Clinical differential diagnoses included basal cell carcinoma, foreign body and cyst.


- Panfolliculoma: hair adnexal neoplasm, differentiates to all elements of the hair follicle

Paywall references

- Panfolliculoma with an endophytic architecture resembling a hair follicle: a report of three cases.
Terushkin V, Meehan S, Shahabi L, Brinster N.
J Cutan Pathol. 2016 Nov;43(11):1074-1076. doi : 10.1111/cup.12799
PMID: 27531523