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ATF1-EWSR1
Friday 13 January 2017
EWSR1-ATF1
Molecular biology
EWSR1-ATF1 fusion gene in hyalinizing clear cell carcinoma of salivary gland (HCCC). (21484932)
- The presence of EWSR1-ATF1 fusion in most HCCCs reliably separates these tumors from its histological mimics.
- The distinction from mucoepidermoid carcinoma (MEC) is particularly important, as conventional MEC grading schemes overgrade these indolent HCCCs, potentially impacting on treatment.
See also : ATF1 and EWSR1
