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poorly cohesive cell carcinoma of the gallbladder
Friday 30 September 2016
Poorly cohesive cell (diffuse-infiltrative/signet-ring cell) carcinomas of the gallbladder
Definition: Signet-ring cell carcinoma is an extremely rare type of gallbladder carcinoma.
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Poorly cohesive cell (diffuse-infiltrative/signet-ring cell) carcinomas of the gallbladder
In the gastrointestinal system, carcinomas with single-cell or cord-like infiltration, previously called “diffuse-infiltrative” type or “signet-ring cell”, are now designated as “poorly cohesive cell” (PCC) type (regardless of with/without signet-ring cells) in the WHO-2010 classification.
PCC carcinoma originating in the gallbladder should be kept in mind for the differential diagnosis of disseminated poorly differentiated carcinomas in the abdomen.
Open references
Primary signet ring cell carcinoma of gall bladder: report of an extremely rare histological type of primary gall bladder carcinoma. Ahmad Z, Qureshi A. BMJ Case Rep. 2010 Sep 7;2010.
doi : 10.1136/bcr.04.2009.1782
PMID: 22778190