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acute generalized exanthematous pustulosis

Tuesday 9 August 2016

AGEP

PO

Definition : AGEP is a pustular drug eruption.

Images

- Acute generalized exanthematous pustulosis (AGEP)

Synopsis

- subcorneal pustules
- spongiosis
- similar to pustular psoriasis but may have rare dermal eosinophils
- scattered epidermal neutrophils
- papillary dermal edema
- mixed dermal perivascular infiltrate, often associating eosinophils and neutrophils
- +/- necrotic keratinocytes

Etiology

- mifepristone-associated acute generalized exanthematous pustulosis

See also

- pustule
- pustulosis / pustuloses