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FLT4

Monday 8 August 2016

Pathology

- FLT4 amplification in angiosarcoma (5%)

  • Utility of FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast. (25864386)
  • Although MYC is a valuable ancillary tool in distinguishing AS from AVL,
  • FLT4 IHC may be used to screen for patients with FLT4 gene amplification who might benefit from targeted therapy.
  • Only diffuse strong FLT4 immunoreactivity correlated with FLT4 gene amplification.

See also

- FLTs
- See also ; MYC , CIC , PLCG1 , KDR