Home > E. Pathology by systems > Skin > eccrine spiradenoma
eccrine spiradenoma
Monday 30 May 2016
| PO |
Definition:
Spiradenoma forms a firm nodule on the face or upper trunk, and can be painful. The lesion is benign.
Images
eccrine spiradenoma
- https://twitter.com/KUSAURAP/status/688570974602575872
- https://twitter.com/drtylerhickey/status/7Au 12333119026647041
- https://twitter.com/RyanHickMD/status/709486901367943168
- https://twitter.com/yamahalion/status/665783302213603329
- https://twitter.com/DrRMalliah/status/746176832127504384
- https://twitter.com/ASDPTweets/status/667192409256685569
- https://twitter.com/Patholwalker/status/1171683029841895425
- https://twitter.com/Patholwalker/status/1214082547941986304
- https://twitter.com/Patholwalker/status/1614732203531042816
cystic eccrine spiradenoma
- https://twitter.com/angeldeoromx/status/720434236969197568
- https://twitter.com/dr_schneiderm/status/592856541839097856
eccrine spiradenoma nodule in the subcutis
Synopsis
nests with two types of cells:
- small hyperchromatic cells at the periphery
- larger and paler cells centrally.
compact PAS+ eosinophilic basement membrane material
infiltrating lymphocytes.
blue nodula formation with biphasic population : peripheral small basaloid cells and larger paler cells centrally
lobulated tumor islands separated by thin fibrous tissue containing blood vessels
benign biphasic basophilic dermal adnexal tumor
- biphasic appearance : light cells and dark cells / basophilic cells
circumscribed nodule (s) with hyaline globules
sharply circumscribed dermal nodule : " blue ball " appearance in dermis
lobular architecture
very cellular / high cellularity
scant cytoplasm
hyaline globules / eosinophilic hyaline droplets
presence of ducts / intratumoral ducts
high vascularity
variable lymphocytic infiltrate within lesion / interstitial lymphocytes
Can occur both separately and in combination with cylindromas
Variants
IHC
CK7+ epithelial and p63+ myoepithelial cells
Differential diagnosis
cutaneous lymphadenoma
cutaneous basaloid cell tumors
- basal cell carcinoma
- cutaneous cylindroma
cutaneous metastatic carcinoma
cutaneous synovial sarcoma
cutaneous thymoma
See also
- cutaneous adnexal tumors
cutaneous nodules / cutaneous nodule
- cutaneous solitary nodule
