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Howell-Jolly body-like inclusions
Monday 30 May 2016
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Howell-Jolly body-like inclusions in neutrophils
Howell-Jolly–like bodies in granulocytes arise secondary to stressed granulopoiesis induced by immunosuppressive drugs, viral infection, or chemotherapy, and must be differentiated from other neutrophil inclusions such as those observed in intracellular bacterial infections, genetic conditions such as Chédiak-Higashi syndrome, or Döhle bodies [Arch Pathol Lab Med. 2003;127(10):1389-1390].
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