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sialadenoma papilliferum
Thursday 19 May 2016
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The sialadenoma papilliferum is a benign biphasic tumor with exophytic squamous component and endophytic glandular component.
Microscopical synopsis
Well differentiated papillary hyperplastic squamous epithelium covering ductal component of cleftlike cystic spaces lined by cuboidal or columnar epithelium with occasional goblet cells.
Biphasic, with well differentiated papillary hyperplastic squamous epithelium covering ductal component of cleftlike cystic spaces lined by cuboidal or columnar epithelium with occasional goblet cells.
Variable oncocytes and squamous metaplasia, dysplasia and in situ carcinoma in exophytic component.
It has malignant counterpart, or evolves to mucoepidermoid carcinoma or epithelial-myoepithelial carcinoma with high grade carcinoma.
Differential diagnosis
papillary syringocystadenoma
Warthin tumor
Open case reports
