Home > A. Molecular pathology > Targeted therapy > BCL2 inhibitors
BCL2 inhibitors
Wednesday 18 May 2016
Examples
venetoclax
- venetoclax is a BH3-mimetic and acts as a Bcl-2 inhibitor.
- It blocks the anti-apoptotic B-cell lymphoma-2 (Bcl-2, BCL2 ) protein, leading to programmed cell death of CLL cells.