discoid lupus

Images

 https://twitter.com/globaldermie/status/726365706359562241

Synopsis

 epidermal hypolasia / epidermal atrophy or epidermal hyperplasia
 attenuation of rete ridges / flattening of rete ridges
 hyperkeratosis and follicular keratotic plugging
 basement membrane thickening
 vacuolar degeneration with keratinocyte apoptosis in the basal layer
 cell poor infiltrate in the papillary dermis in most cases
 lichenoid infiltrate / band-like infiltrate composed of lymphocytes in some cases
 dermal dilated blood vessels
 dermal edema
 dermal pigmentary incontinence
 dense superficial and deep dermal lymphocytic infiltrate around the adnexae and vessels

• periadnexal lymphocytic infiltrate
• perivascular lymphocytic infiltrate

 increased plasma cells in dermis
 increased mucin in dermis
 pilosebaceous unit damage and broad zones of dermal fibrosis

See also

 cutaneous diseases