renal clear cell anomalies

Types

 non-neoplastic clear cell anomalies

• xanthogranulomatous pyelonephritis

 benign/Low malignant potential clear cell anomalies

• cystic nephroma
• multilocular cystic renal cell neoplasm of low malignant potential (MCRCNLMP) (previously "cystic clear cell RCC")

 malignant lesions

• clear cell renal cell carcinoma (ccRCC)
• clear cell tubulopapillary renal cell carcinoma
• TCEB1-mutated renal cell carcinoma (monosomy 8)
• papillary renal cell carcinoma with clear cell features
• Xp11.2 translocation renal cell carcinoma
• chromophobe renal cell carcinoma
• clear cell metastatic tumors
  • clear cell adrenal cortical carcinoma
  • ovarian clear cell carcinoma

Immunochemistry

	CK7	AMACR	CD10	CAIX	TFE3
CCRCC	Neg	Var	Pos	Pos	Neg
CCTPRCC	P.	Neg	Neg	Pos	Neg
TCEEll-RCC	Pos	Var	Var	P.	Neg
PRCC	P.	P.	P.	Neg	Neg
Xp11.2 RCC	Neq	P.	Var	Neq	Pos
ChRCC	Var	Var	Neg	Neg	Neg