Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > Tumoral translocations > t(5;14)(q31;q32)
t(5;14)(q31;q32)
Tuesday 8 March 2016
IL3-IgH fusion
Tumors
B-lymphoblastic lymphoma
— hypereosinophilia and acute endocarditis.
— IL3 hypersecretion and hypereosinophilia.
Images
https://twitter.com/evemariecrane/status/679715283020451840
Open references
The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene. Grimaldi JC, Meeker TC. Blood. 1989 Jun;73(8):2081-5. PMID: 2499362
