- Human pathology

Home > A. Molecular pathology > Systems medicine > diseasome


Monday 12 October 2015

See aslo

- disease module
- disease network
- diseasomics
- cancerome

Open references

- Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types. Cornish AJ, Filippis I, David A, Sternberg MJ. Genome Med. 2015 Sep 1;7(1):95. doi : 10.1186/s13073-015-0212-9 PMID: 26330083 (Free)

- The human disease network in terms of dysfunctional regulatory mechanisms. Yang J, Wu SJ, Dai WT, Li YX, Li YY. Biol Direct. 2015 Oct 8;10(1):60. doi : 10.1186/s13062-015-0088-z PMID: 26450611 (Free)

- Analysis of the human diseasome using phenotype similarity between common, genetic, and infectious diseases. Hoehndorf R, Schofield PN, Gkoutos GV. Sci Rep. 2015 Jun 8;5:10888. doi : 10.1038/srep10888 PMID: 26051359 (Free)

- Mining the diseasome. Urbach D, Moore JH. BioData Min. 2011 Sep 9;4:25. doi : 10.1186/1756-0381-4-25 PMID: 21906309

- Interactome networks and human disease. Vidal M, Cusick ME, Barabási AL.
Cell. 2011 Mar 18;144(6):986-98. doi : 10.1016/j.cell.2011.02.016 PMID: 21414488 (Free)

- When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases. Navratil V, de Chassey B, Combe CR, Lotteau V. BMC Syst Biol. 2011 Jan 21;5:13. doi : 10.1186/1752-0509-5-13 PMID: 21255393 (Free)

- The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome. Nagaraj SH, Ingham A, Reverter A. BMC Genomics. 2010 Dec 2;11 Suppl 4:S23. doi : 10.1186/1471-2164-11-S4-S23 PMID: 21143807 (Free)

- Protein disorder in the human diseasome: unfoldomics of human genetic diseases.
Midic U, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN. BMC Genomics. 2009 Jul 7;10 Suppl 1:S12. doi : 10.1186/1471-2164-10-S1-S12 PMID: 19594871 (Free)

- A pathway-based view of human diseases and disease relationships. Li Y, Agarwal P. PLoS One. 2009;4(2):e4346. doi : 10.1371/journal.pone.0004346 PMID: 19194489 (Free)

- Network medicine—from obesity to the "diseasome". Barabási AL. N Engl J Med. 2007 Jul 26;357(4):404-7. PMID: 17652657 (Free)

- Inferring pathways from gene lists using a literature-derived network of biological relationships. Rajagopalan D, Agarwal P. Bioinformatics. 2005 Mar;21(6):788-93. PMID: 15509611 (Free)


- Disease networks. Uncovering disease-disease relationships through the incomplete interactome. Menche J, Sharma A, Kitsak M, Ghiassian SD, Vidal M, Loscalzo J, Barabási AL. Science. 2015 Feb 20;347(6224):1257601. doi : 10.1126/science.1257601 PMID: 25700523

- Systematic large-scale study of the inheritance mode of Mendelian disorders provides new insight into human diseasome. Hao D, Wang G, Yin Z, Li C, Cui Y, Zhou M.
Eur J Hum Genet. 2014 Nov;22(11):1260-7. doi : 10.1038/ejhg.2013.309 PMID: 24448549

- Human symptoms-disease network. Zhou X, Menche J, Barabási AL, Sharma A. Nat Commun. 2014 Jun 26;5:4212. doi : 10.1038/ncomms5212 PMID: 24967666

- Exploring the human diseasome: the human disease network. Goh KI, Choi IG. Brief Funct Genomics. 2012 Nov;11(6):533-42. doi : 10.1093/bfgp/els032 PMID: 23063808

- The expanded human disease network combining protein-protein interaction information. Zhang X, Zhang R, Jiang Y, Sun P, Tang G, Wang X, Lv H, Li X. Eur J Hum Genet. 2011 Jul;19(7):783-8. PMID: 21386875

- Diseasome: an approach to understanding gene-disease interactions. Wysocki K, Ritter L. Annu Rev Nurs Res. 2011;29:55-72. PMID: 22891498

- Unfoldomics of human genetic diseases: illustrative examples of ordered and intrinsically disordered members of the human diseasome. Midic U, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN. Protein Pept Lett. 2009;16(12):1533-47. PMID: 20001916

- Barabási AL. Network medicine—from obesity to the "diseasome". N Engl J Med. 2007 Jul 26;357(4):404-7. PMID: 17652657

- Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabási AL. The human disease network. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8685-90. PMID: 17502601

- Loscalzo J, Kohane I, Barabasi AL. Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.Mol Syst Biol. 2007;3:124. PMID: 17625512