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hepatic arteriolosclerosis

Tuesday 24 March 2015

Hepatic arteriolosclerosis is a small-vessel complication (microangiopathy) of the liver observed mainly in patients with diabetes who also have arterial hypertension. The clinical and prognostic implications of this finding, particularly regarding liver injury, remain to be further investigated.

Liver involvement in diabetes is well recognized in the form of steatohepatitis and glycogenic hepatopathy. More recently, sinusoidal fibrosis, even in the absence of steatosis, has also been suggested to be associated with diabetes (diabetic hepatosclerosis).

Reference

- Hepatic Arteriolosclerosis: A Small-vessel Complication of Diabetes and Hypertension. Balakrishnan M, Garcia-Tsao G, Deng Y, Ciarleglio M, Jain D. Am J Surg Pathol. 2015 Mar 16. PMID: 25786083