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invasive endocervical adenocarcinoma
Thursday 5 March 2015
Images
63yo with atypical glandular cells on pap smear, endocervical adenocarcinoma
Classification system
A new 3-tier pattern-based system to classify endocervical adenocarcinoma was recently presented.
Pattern A tumors were characterized by well-demarcated glands frequently forming clusters or groups with relative lobular architecture.
Pattern B tumors demonstrated localized destructive invasion defined as desmoplastic stroma surrounding glands with irregular and/or ill-defined borders or incomplete glands and associated tumor cells (individual or small clusters) within the stroma.
Tumors with pattern C showed diffusely infiltrative glands with associated extensive desmoplastic response.
See also
endocervical adenocarcinoma
References
Invasive Endocervical Adenocarcinoma: A New Pattern-based Classification System With Important Clinical Significance. Roma AA, Diaz De Vivar A, Park KJ, Alvarado-Cabrero I, Rasty G, Chanona-Vilchis JG, Mikami Y, Hong SR, Teramoto N, Ali-Fehmi R, Rutgers JK, Barbuto D, Silva EG. Am J Surg Pathol. 2015 Feb 25. PMID: 25724003
