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anomalies associated with breast implants

Monday 2 March 2015

Images

- silicone lymphadenopathy

- silicone granuloma

Anomalies

- silicone foreign body reaction / silicone granuloma
- capsular synovial-like hyperplasia around mammary implants similar to detritic synovitis (7694944)
- silicone lymphadenopathy ( 3377110)

- anaplastic large cell lymphoma (ALCL) of the breast (18594466)

  • Primary lymphomas of the breast are rare and predominately of B-cell phenotype.
  • Anaplastic large cell lymphoma is a T-cell lymphoma that accounts for only 3% of all non-Hodgkin lymphomas.
  • Rare cases of primary anaplastic large cell lymphoma (ALCL) of the breast have been described in association with a silicone breast implant capsule.

- follicular lymphoma adjacent to foreign body granulomatous inflammation and fibrosis surrounding silicone breast prosthesis. (7755157)

References

- Anaplastic large cell lymphoma associated with a breast implant capsule: a case report and review of the literature. Wong AK, Lopategui J, Clancy S, Kulber D, Bose S. Am J Surg Pathol. 2008 Aug;32(8):1265-8. doi : 10.1097/PAS.0b013e318162bcc1 PMID: 18594466

- Pathology of lymph nodes from patients with breast implants: a histologic and spectroscopic evaluation. Katzin WE, Centeno JA, Feng LJ, Kiley M, Mullick FG. Am J Surg Pathol. 2005 Apr;29(4):506-11; PMID: 15767806

- Follicular lymphoma adjacent to foreign body granulomatous inflammation and fibrosis surrounding silicone breast prosthesis. Cook PD, Osborne BM, Connor RL, Strauss JF. Am J Surg Pathol. 1995 Jun;19(6):712-7. PMID: 7755157

- Capsular synovial-like hyperplasia around mammary implants similar to detritic synovitis. A morphologic and immunohistochemical study of 15 cases. Hameed MR, Erlandson R, Rosen PP. Am J Surg Pathol. 1995 Apr;19(4):433-8. PMID: 7694944

- Silicone lymphadenopathy associated with augmentation mammaplasty. Morphologic features of nine cases. Truong LD, Cartwright J Jr, Goodman MD, Woznicki D. Am J Surg Pathol. 1988 Jun;12(6):484-91. PMID: 3377110

- Peri-articular reactions to microscopic erosion of silicone-polymer implants. Light- and scanning electron-microscopic studies with energy-dispersive x-ray analysis. Yamashina M, Moatamed F. Am J Surg Pathol. 1985 Mar;9(3):215-9. PMID: 3993833