hemangiomas

Digital slides

 UI:717 - Hemangioma (NOS) in soft tissue of the breast

Classification

 congenital hemangioma

• rapidly involuting congenital hemangioma (RICH)
• non-involuting congenital hemangioma (NICH)

 GLUT1+ infantile hemangioma
 tufted hemangioma (MIM.607859)
 hemangioma targetoid hemosiderotic hemangioma
 lobular capillary hemangioma (pyogenic granuloma)
 epithelioid hemangioma

 hemangioendotheliomas

• kaposiform hemangioendothelioma (KHE)
• fusiform hemangioendothelioma
• epithelioid hemangioendothelioma

 capillary hemangioblastoma

Localization

 cutaneous hemangiomas
 visceral hemangiomas

• pulmonary hemangiomas
• digestive hemangiomas
• hepatic hemangiomas

Predisposition syndromes to hemangiomas

 von Hippel-Lindau disease (retinal, pulmonary, hepatic, adrenal) (MIM.193300)
 glycogen storage disease type 1c (skin spider hemangioma) (MIM.232240)
 blue rubber bleb nevus (MIM.112200)

Molecular biology

 LOH 5q (11253142)

Cytogenetics

 trisomy 5 (2278963)
 loss of the Y chromosome (2278963)

See also

 hemangiomatoses (hemangiomatosis)

References

 Vikkula M, Boon LM, Mulliken JB, Olsen BR. Molecular basis of vascular anomalies. Trends Cardiovasc Med. 1998 Oct;8(7):281-92. PMID: 14987552