high-grade dysplasia in Barrett esophagus

Images

 High grade dysplasia in Barrett esophagus

• http://www.webpathology.com/image.asp?n=6&Case=185

 High grade dysplasia in Barrett esophagus with strong nuclear TP53 immunolabeling

• https://twitter.com/ARP_Press/status/847587416995016704

Dysplasia in Barrett esophagus is dividied into low-grade and high-grade. Dysplastic changes are most often seen in the areas of incomplete intestinal metaplasia.

In high-grade dysplasia, he glands are crowded and irregularly shaped and there is nuclear hyperchromasia, increased mitotic activity, and prominent nucleoli.