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low-grade dysplasia in Barrett esophagus
Tuesday 16 April 2013
Barrett Esophagus : Low-grade Dysplasia; BE
Images
http://www.webpathology.com/image.asp?case=185&n=5
Low grade dysplasia in Barrett esophagus resembling a tubular adenoma
Barrett esophagus is a pre-malignant condition. It is important to look for dysplasia when Barrett esophagus is diagnosed. Dysplastic changes consist of both cytologic as well as architectural atypia.
Cytologic changes include nuclear hyperchromasia and stratification, irregularly clumped chromatin, increased N:C ratios, increased mitotic activity including abnormal mitotic figures, and loss of polarity.
See also
Vienna classification in Barrett esophagus dysplasia
epithelial dysplasia in Barrett esophagus
Open references
Revised British Society of Gastroenterology recommendation on the diagnosis and management of Barrett’s oesophagus with low-grade dysplasia. 2017. doi : 10.1136/gutjnl-2017-314135
Fitzgerald RC, Di Pietro M, Ragunath K, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett’s oesophagus. Gut 2014;63:7–42. doi : 10.1136/gutjnl-2013-305372
