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myxoid soft tissue tumors

Wednesday 10 April 2013

soft tissue myxoid tumors; myxoid tumors of soft tissues; myxoid lesions of soft tissue; soft tissue myxoid tumors; myxoid tumours of soft tissue

Definition: Myxoid tumours of soft tissue encompass a heterogeneous group of lesions characterized by a marked abundance of extracellular mucoid (myxoid) matrix.


- Circumscribed myxoid lesion of finger by Ed Euthman

- Ossifying fibromyxoid tumour, male, 60yo, right thigh


Benign Locally aggressive Malignant
dermal myxoma juxta-articular myxoma myxofibrosarcoma
superficial angiomyxoma aggressive angiomyxoma low-grade fibromyxoid sarcoma
Ganglion ( low-grade myxofibrosarcoma ) myxoid liposarcoma
myxoid nodular fasciitis (Atypical OFMT) extraskeletal myxoid chondrosarcoma
myxoid neurofibroma myxoid leiomyosarcoma
myxolipoma myxoid MPNST
dermal nerve sheath myxoma myxoid DFSP
intramuscular myxoma myxopapillary ependymoma
ossifying fibromyxoid tumour (OFMT)

Differential diagnosis

- myxofibrosarcoma
- myxoid fibroblastic sarcoma
- intramuscular myxoma
- myxoid liposarcoma

Diagnostic approach

- Size
- Level
- Architecture
- Vessels
- Cellularity
- Atypia
- Immunohistochemistry and/or molecular pathology


Dermal dermal nerve sheath myxoma superficiel angiomyxoma digital myxoma digital fibromyxoma
Subcutaneous nodular fasciitis, myxoid type myxofibrosarcoma ossifying fibromyxoid tumor (acral) myxoinflammatory fIbroblastic sarcoma Intra-muscular intramuscular low-grade fibromyxoid sarcoma myxoid liposarcoma deep angiomyxoma


- superficial acral fibromyxoma



See also

- myxoid tumors
- soft tissue tumors


- Myxoid tumours of soft tissue. Graadt van Roggen JF, Hogendoorn PC, Fletcher CD. Histopathology. 1999 Oct;35(4):291-312. PMID: 10564384