Humpath.com - Human pathology

Home > E. Pathology by systems > Reproductive system > Female genital system > Uterus > Uterine cervix > ASC-US

ASC-US

Monday 8 April 2013

ASCUS : Atypical squamous cells of undetermined significance

WHO : https://screening.iarc.fr/atlasglossdef.php?key=ASC-US&img

Types

- intermediate cell with an enlarged nucleus and a homogenous chromatin
- eosinophilic squamous cell with enlarged and hyperchromatic nucleus
- eosinophilic squamous cell with an enlarged nucleus but with pale chromatin
- intermediate cells with an enlarged nucleus and a chromatin slightly denser
- squamous cell with eosinophilic cytoplasm and an enlarged nucleus and a non densified chromatin
- intermediate squamous cell with an enlarged nucleus and a cytoplasmic clearing
- basophilic squamous cells with enlarged and slightly hyperchromatic nuclei
- eosinophilic squamous cells with enlarged nuclei and cytoplasmic clearing
- intermediate cell with an enlarged, regular nucleus and a homogenous chromatin, surrounded by an ill-defined clear halo
- binucleated eosinophilic cell with a dense, homogenous chromatin
- squamous metaplastic cells from the deep intermediate layers with nuclear enlargement
- superficial eosinophilic cell with enlarged and irregular nucleus
- intermediate cell with a mildly densifiied and an enlarged nucleus with a small perinuclear halo

Images

- https://screening.iarc.fr/atlascyto_detail.php?flag=0&lang=1&Id=cyt14536&cat=F1a1a

Differential diagnosis

- CIN 3 Pap/Biopsy Correlation Case by Ed Euthman

See also

- ASC : atypical squamous cells

  • ASC-H : atypical squamous cells cannot exclude HSIL