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prostatic adenocarcinoma with focal mucin extravasation

Wednesday 1 August 2012

prostate adenocarcinoma with focal mucin extravasation

There was consensus amongst the group that adenocarcinomas of the prostate with focal mucinous extravasation should not be by default graded as Gleason score 4+4=8.

Rather, one should ignore focal mucinous extravasation and grade the tumor based on the underlying architecture of the glands.

The distinction between focal mucinous extravasation and colloid carcinoma is the presence of epithelial elements floating within the mucinous matrix within the latter whereas with mucinous extravasation there is only focal acellular mucin adjacent to cancer.