HIV

Pahology (HIV infection)

 AIDS
 HIV-associated oral lesions
 HIV-associated vasculopathy
 HIV-associated lymphoproliferative disorders

• HIV-associated polymorphic lymphoproliferative disorders
• HIV-associated lymphomas

Video

 HIV

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/XfEJW2lyTeY">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/XfEJW2lyTeY" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 HIV biology

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/oPC-Dc0fRac">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/oPC-Dc0fRac" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 HIV replication

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/0SOzJVrqBbU">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/0SOzJVrqBbU" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 HIV infection of a cell

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/FErrWXDRD7o">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/FErrWXDRD7o" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 Targeting HIV Replication

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/t4zjTeAGyuk">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/t4zjTeAGyuk" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 HIV resistance

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/QS1iQgOEbgM">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/QS1iQgOEbgM" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

 HIV Life Cycle

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/O8thgFLpRNk">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/O8thgFLpRNk" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

References

 De Clercq E. The design of drugs for HIV and HCV. Nat Rev Drug Discov. 2007 Dec;6(12):1001-18. PMID: 18049474

 Lieberman J, Manjunath N, Shankar P. Avoiding the kiss of death: how HIV and other chronic viruses survive. Curr Opin Immunol. 2002 Aug;14(4):478-86. PMID: 12088683

 Rose KM, Marin M, Kozak SL, Kabat D. The viral infectivity factor (Vif) of HIV-1 unveiled. Trends Mol Med. 2004 Jun;10(6):291-7. PMID: 15177194

 Rambaut A, Posada D, Crandall KA, Holmes EC. The causes and consequences of HIV evolution. Nat Rev Genet. 2004 Jan;5(1):52-61.PMID: 14708016

 Fischer A. Human primary immunodeficiency diseases: a perspective. Nat Immunol. 2004 Jan;5(1):23-30. PMID: 14699405

 Amara RR, Robinson HL. A new generation of HIV vaccines. Trends Mol Med. 2002 Oct;8(10):489-95. PMID: 12383772

 Shields R, Dell H. Genes for HIV susceptibility. Trends Genet. 2001 Jan;17(1):19. PMID: 11163915

 Carrington M, Dean M, Martin MP, O’Brien SJ. Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences. Hum Mol Genet. 1999;8(10):1939-45. PMID: 10469847