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cancer whole-genome sequencing
Sunday 17 April 2011
cancer WGS, WCGS, oncogenome, whole cancer genome sequencing; cancer genome sequencing, oncogenome sequencing
Videos
Comparison of primary and metastatic acral melanoma by whole genome sequencing
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Video: Greg Tyrelle - Complete Genomics - Whole Oncogenome Sequencing: Is tomorrow today?
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See also
cancer exome sequencing
Reviews
Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Leary RJ, Sausen M, Kinde I, Papadopoulos N, Carpten JD, Craig D, O’Shaughnessy J, Kinzler KW, Parmigiani G, Vogelstein B, Diaz LA Jr, Velculescu VE. Sci Transl Med. 2012 Nov 28;4(162):162ra154. doi : 10.1126/scitranslmed.3004742 PMID: 23197571
Whole cancer genome sequencing by next-generation methods. Ross JS, Cronin M. Am J Clin Pathol. 2011 Oct;136(4):527-39. PMID: 21917674
Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Cronin M, Ross JS. Biomark Med. 2011 Jun;5(3):293-305. Review. PMID: 21657839
Advances in understanding cancer genomes through second-generation sequencing. Meyerson M, Gabriel S, Getz G. Nat Rev Genet. 2010 Oct;11(10):685-96. PMID: 20847746
References
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Fujimoto A, Totoki Y, Abe T, Boroevich KA et al. Nat Genet. 2012 May 27;44(7):760-4. doi : 10.1038/ng.2291 PMID: 22634756
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Molenaar JJ, Koster J, Zwijnenburg DA, van Sluis P, Valentijn LJ, van der Ploeg I, Hamdi M, van Nes J, Westerman BA, van Arkel J, Ebus ME, Haneveld F, Lakeman A, Schild L, Molenaar P, Stroeken P, van Noesel MM, Ora I, Santo EE, Caron HN, Westerhout EM, Versteeg R. Nature. 2012 Feb 22;483(7391):589-93. doi : 10.1038/nature10910 PMID: 22367537
Whole-genome reconstruction and mutational signatures in gastric cancer. Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ et al. Genome Biol. 2012 Dec 13;13(12):R115. PMID: 23237666
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Puente XS, Pinyol M, Quesada V et al. Nature. 2011 Jun 5;475(7354):101-5. PMID: 21642962
