esophageal tumors

Types - WHO histological classification of oesophageal tumours

 esophageal epithelial tumors

• esophageal squamous cell papilloma 8052/01
• esophageal intraepithelial neoplasia
  • esophageal squamous intraepithelial neoplasia
  • esophageal glandular intraepithelial neoplasia (adenoma)

• esophageal carcinoma
  • esophageal squamous cell carcinoma 8070/3
  • esophageal verrucous (squamous) carcinoma 8051/3
  • esophageal basaloid squamous cell carcinoma 8083/3
  • esophageal spindle cell (squamous) carcinoma 8074/3
  • esophageal adenocarcinoma 8140/3
  • esophageal adenosquamous carcinoma 8560/3
  • esophageal mucoepidermoid carcinoma 8430/3
  • esophageal adenoid cystic carcinoma 8200/3
  • esophageal small cell carcinoma 8041/3
  • esophageal undifferentiated carcinoma 8020/3
  • Others

• esophageal carcinoid tumor 8240/3

• esophageal non-epithelial tumors
  • esophageal leiomyoma 8890/0
  • esophageal lipoma 8850/0
  • esophageal granular cell tumour 9580/0
  • esophageal gastrointestinal stromal tumour 8936/1
    • benign 8936/0
    • uncertain malignant potential 8936/1
    • malignant 8936/3

• • esophageal leiomyosarcoma 8890/3
  • esophageal rhabdomyosarcoma 8900/3
  • esophageal Kaposi sarcoma 9140/3
  • esophageal melanoma 8720/3
  • Others

• esophageal secondary tumors

TNM classification of esophageal tumors

This classification applies only to carcinomas.

T – Primary Tumour
 TX Primary tumour cannot be assessed
 T0 No evidence of primary tumour
 Tis Carcinoma in situ
 T1 Tumour invades lamina propria or submucosa
 T2 Tumour invades muscularis propria
 T3 Tumour invades adventitia
 T4 Tumour invades adjacent structures

N – Regional Lymph Nodes
 NX Regional lymph nodes cannot be assessed
 N0 No regional lymph node metastasis
 N1 Regional lymph node metastasis

M – Distant Metastasis
 MX Distant metastasis cannot be assessed
 M0 No distant metastasis
 M1 Distant metastasis

For tumours of lower thoracic oesophagus
 M1a Metastasis in coeliac lymph nodes
 M1b Other distant metastasis

For tumours of upper thoracic oesophagus
 M1a Metastasis in cervical lymph nodes
 M1b Other distant metastasis

For tumours of mid-thoracic oesophagus
 M1a Not applicable
 M1b Non-regional lymph node
or other distant metastasis

Stage Grouping

 Stage 0 Tis N0 M0
 Stage I T1 N0 M0
 Stage IIA T2 N0 M0 or T3 N0 M0
 Stage IIB T1 N1 M0 or T2 N1 M0
 Stage III T3 N1 M0 or T4 Any N M0
 Stage IVA Any T Any N M1a
 Stage IVB Any T Any N M1b