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systemic lupus erythematosus-associated lymphoproliferative disorder
Monday 24 January 2011
Histological examination reveals a polymorphous lymphoid infiltrate containing many plasma cells, rare immunoblasts, and a pronounced arborizing vasculature.
In one case, no foci of necrosis were found and there was no evidence of lymphocyte depletion.
The unusual gross features, which resembled a malignant lymphoproliferative process, as well as the unusual histological features make this entity a notable addition to the spectrum of atypical lymphoproliferative disorders associated with an autoimmune disorder.
See also
autoimmune disease-associated lymphadenopathy (ADAL)
References
Systemic lupus erythematosus-associated lymphoproliferative disorder: report of a case and discussion in light of the literature. Blanco R, McLaren B, Davis B, Steele P, Smith R. Hum Pathol. 1997 Aug;28(8):980-5. PMID: 9269836
