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DSD-associated tumors
Wednesday 19 January 2011
The newly recognized "undifferentiated gonadal tissue" has been identified as a gonadal differentiation pattern bearing a high risk for the development of gonadoblastoma.
References
Tumor risk in disorders of sex development. Pleskacova J, Hersmus R, Oosterhuis JW, Setyawati BA, Faradz SM, Cools M, Wolffenbuttel KP, Lebl J, Drop SL, Looijenga LH. Sex Dev. 2010 Sep;4(4-5):259-69. PMID: 20558977
Gonadal tumours and DSD. Looijenga LH, Hersmus R, de Leeuw BH, Stoop H, Cools M, Oosterhuis JW, Drop SL, Wolffenbuttel KP. Best Pract Res Clin Endocrinol Metab. 2010 Apr;24(2):291-310. PMID: 20541153
New insights into type II germ cell tumor pathogenesis based on studies of patients with various forms of disorders of sex development (DSD). Hersmus R, de Leeuw BH, Wolffenbuttel KP, Drop SL, Oosterhuis JW, Cools M, Looijenga LH. Mol Cell Endocrinol. 2008 Sep 10;291(1-2):1-10. PMID: 18403106
Tumor risk in disorders of sex development (DSD). Looijenga LH, Hersmus R, Oosterhuis JW, Cools M, Drop SL, Wolffenbuttel KP. Best Pract Res Clin Endocrinol Metab. 2007 Sep;21(3):480-95. PMID: 17875493
Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiers. Cools M, Drop SL, Wolffenbuttel KP, Oosterhuis JW, Looijenga LH. Endocr Rev. 2006 Aug;27(5):468-84. PMID: 16735607 [Free]
