myxoinflammatory fibroblastic sarcoma
Myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor are rare, slow-growing soft tissue tumors of the distal extremities with recurrent potential.
Recent cytogenetic studies have shown a t(1;10)(p22;q24) or der(10)t(1;10) in combination with aberrations of chromosome 3 in a limited number of cases of both entities.
In a soft tissue tumor of the ankle showing hybrid morphologic features of myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor, a der(10)t(1;10), and abnormalities of chromosome 3 have been described. This hybrid lesion provides further evidence for a close relationship between these 2 tumor types.
See also
hemosiderotic fibrolipomatous tumor
References
Hybrid myxoinflammatory fibroblastic sarcoma/hemosiderotic fibrolipomatous tumor: report of a case providing further evidence for a pathogenetic link. Elco CP, Mariño-Enríquez A, Abraham JA, Dal Cin P, Hornick JL. Am J Surg Pathol. 2010 Nov;34(11):1723-7. PMID: #20871391#