Humpath.com - Human pathology

Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > CGH anomalies > CGH losses > 6q loss

6q loss

Thursday 9 September 2010

- Chromosome arm 6q loss is the most common recurrent autosomal alteration detected in primary pediatric ependymoma.

- Loss of chr 6q is mainly observed in infratentorial ependymoma and World Health Organization (WHO) grade 3 ependymomas.

References

- Reardon DA, Entrekin RE, Sublett J, Ragsdale S, Li H, Boyett J, Kepner JL, Look AT (1999) Chromosome arm 6q loss is the most common recurrent autosomal alteration detected in primary pediatric ependymoma. Genes Chromosomes Cancer 24:230–237