Home > D. Systemic pathology > Genetic and developmental anomalies > recombination hot spots
recombination hot spots
Sunday 7 March 2010
Recombination, together with mutation, generates the raw material of evolution, is essential for reproduction and lies at the heart of all genetic analysis.
Trans-acting systems that regulate the location and relative activity of individual hot spots have been identified.
References
Mammalian recombination hot spots: properties, control and evolution. Paigen K, Petkov P. Nat Rev Genet. 2010 Mar;11(3):221-33. PMID: 20168297
