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Q fever

Monday 1 February 2010

Definition: Q fever is a zoonotic infection caused by Coxiella burnetii. Two forms of the disease have been described: an acute form with pneumonia, hepatitis or a flu-like syndrome; and a chronic form in which endocarditis is the most frequent clinical expression.


- granulomatous lobular panniculitis (19751228)

- fibrin-ring granulomas in the liver or the bone marrow

  • granulomas rimmed by an eosinophilic material, giving a "doughnut" or "fibrin-ring" appearance.


- Histopathology of a granulomatous lobular panniculitis in acute Q fever: a case report. Soulard R, Souraud J, Landais C, Le Hemon A, Gaillard T, Fouet B. J Cutan Pathol. 2009 Sep 14. PMID: 19751228