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uterine spindle cell tumors
Saturday 9 May 2009
uterine fusiform cell tumors
Differential diagnosis
low-grade endometrial stromal sarcoma ( LGESS )
endometrial stromal nodule
- endometrial stromal nodule has large, thick-walled blood vessels with muscular walls.
- Endometrial stromal nodule is non-invasive.
- IHC is positive by IHC for CD10, ER, PR, androgen receptor, B-catenin, WT1, CK, vimentin, and muscle markers including muscle-specific actin and SMA.
uterine cellular leiomyoma
- Cellular leiomyoma has large, thick walled blood vessels with muscular walls, lacks atypia and mitoses.
uterine leiomyosarcoma
- Leiomyosarcoma is positive by IHC for desmin, SMA, myosin, ER, PR, EMA and Ki-67, and is invasive.
See also
spindle cell tumors
uterine tumors