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hobnail-like cell

Friday 8 May 2009

Hobnail-like cells, which suggest a diagnosis of ovarian clear cell carcinoma, are also focally observed in serous borderline tumor of the ovary, causing diagnostic confusion.

However, the precise nature of hobnail-like cells in serous borderline tumor has not been well characterized.

Hobnail-like cells in serous borderline tumor do not represent concomitant incipient clear cell neoplasms because (1) clear cell carcinoma and serous borderline tumor do not coexist and (2) hobnail-like cells in clear cell carcinoma and serous borderline tumor are immunophenotypically distinct. (19368953)

References

- Hobnail-like cells in serous borderline tumor do not represent concomitant incipient clear cell neoplasms. Ohishi Y, Oda Y, Kurihara S, Kaku T, Yasunaga M, Nishimura I, Okuma E, Kobayashi H, Wake N, Tsuneyoshi M. Hum Pathol. 2009 Apr 13. PMID: 19368953