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Thursday 19 March 2009


Definition: The cryoglobulins are immunoglobulins that precipitate as serum is cooled below core body temperature.1 Precipitation may occur just below 37°C or not until the serum is cooled to near 4°C. Some cryoglobulins precipitate within a few hours and others may take 2-3 days before they precipitate at 4°C, therefore, cryoglobulin determination is made atleast 72 hours after the serum is maintained at 4°C.


- UPMC #593

- in skin vessels

- cryoglobuliemia-asscociated glomerulonephritis

See also

- vasculitis

  • vasculitides