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invasive micropapillary serous carcinoma
Wednesday 24 September 2008
Invasive micropapillary serous carcinoma (MPSC) also designated "low-grade serous carcinoma" (LGSC) of the ovary is characterized by small micropapillae that infiltrate underlying tissue (ovarian stroma).
On occasion these tumors in addition to the micropapillae contain large macropapillae lined by bland epithelium.
In rare cases, the entire tumor is composed of macropapillae. In these cases, the question of whether this is an invasive carcinoma or an unusual type of adenofibroma has been raised. (18779727)
The finding of macropapillae within lymph nodes supports the interpretation that the macropapillary component is another manifestation of invasion in LGSC.
The recognition of this pattern is important, especially in cases when a tumor is composed entirely of macropapillae. (18779727)
See also
ovarian adenocarcinomas
References
Yemelyanova A, Mao TL, Nakayama N, Shih IM, Kurman RJ. Low-grade Serous Carcinoma of the Ovary Displaying a Macropapillary Pattern of Invasion. Am J Surg Pathol. 2008 Sep 5. PMID: 18779727