Home > A. Molecular pathology > SLC5A2
SLC5A2
MIM.182381 16p11.2
Wednesday 6 August 2008
The major reabsorptive mechanism for D-glucose in the kidney is known to involve a lower affinity, high capacity Na(+)/glucose cotransporter, which is located in the early proximal convoluted tubule segment S1 and has a Na(+)-to-glucose coupling ratio of 1:1.
Pathology
germline mutation in the sodium/glucose cotransporter SGLT2 encoded by the SLC5A2 gene (MIM.182381) in autosomal recessive renal glucosuria (MIM.233100)
See also
SLCs
- SLC5s
