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sulfatide

Definition: Sulfatides (or sulfolipids) are a class of sulfated galactosylceramides (galactocerebroside) synthesized primarily in the oligodendrocytes in the central nervous system.

Pathology

Alterations in sulfatide metabolism, trafficking, and homeostasis are present in the earliest clinically recognizable stages of Alzheimer disease and are associated with metachromatic leukodystrophy (MLD).

See also

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