M1G
M1G (pyrimido[1,2-a]purin-10(3H)-one) is a DNA adduct.
M1G is created by malondialdehyde (an end product of lipid peroxidation) and is mutagenic. It is repaired by the body by the nucleotide excision repair system. If not repaired, the adduct is mutagenic.
Therefore, detection and quantification of M1G adducts in the body can be done.
M1G has been detected in cell DNA in liver, leucocytes, pancreas and breast in concentrations of 1-120 per 108 nucleotides.