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ameloblastic fibro-odontoma

Wednesday 21 May 2008

Definition : Ameloblastic fibro-odontoma (AFO) is a quite rare, mixed odontogenic tumour generally seen in the early stages of life. Ameloblastic fibro-odontomas usually present in young adults in the posterior jaws.

Radiographically they may be unilocular or multilocular but are well circumscribed with a corticated border with a mixed radiolucency/radio-opacity appearance.

Microscopy

- numerous cords and follicles of odontogenic epithelium exhibiting peripheral ameloblast-like cells within primitive ectomesenchymal tissue
- Hard tissue examination exhibited conglomerate mass of enamel and dentine arranged in a disorganized pattern and in close relationship to the ameloblastic epithelium
- follicles of amelobalstic epithelium within a primitive ectomesenchyme
- island and cords of cuboidal epithelium
- myxoid background
- Mineralization is seen with enamel, dentin and cementum formation.

  • The mineralized material may be organized to resemble poorly formed teeth.
  • enamel and dentine in close relationship with the ameloblastic epithelium.

These lesions are treated conservatively with simple curettage and recurrences are rare.

Ameloblastic fibro-odontoma has features of ameloblastic fibroma but in addition they have enamel and dentin deposition.

Ameloblastic fibro-dentinoma is best regard as a variant of ameloblastic fibro-odontoma and has only dentin deposition.

See also

- ameloblastic tumors
- odontogenic tumors
- odontogenic cysts

Open references

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276268/ 2014