B-cell lymphomas

Types

 small B-cell lymphomas

• nodular small B-cell lymphomas
  • CD5+: mantle cell lymphoma (CyD1+, BCL6-, CD10-)
  • CD5- follicular lymphoma (BCL2+, BCL6+, CD10+)

• diffuse small B-cell lymphomas
  • CD5+ diffuse small B-cell lymphomas
    • CD5+, CD23+: lymphocytic lymphoma
    • CD5+, CD23-, CyD1+: mantle cell lymphoma (CyD1+, BCL6-, CD10-)

• • CD5- diffuse small B-cell lymphomas
    • CD5-, BCL6-, CD10-, CD23- : marginal zone lymphoma (MALT lymphoma)
    • CD5-, CD79a+, Ig+: lymphoplasmocytic lymphoma

 large B-cell lymphomas

• nodular large B-cell lymphomas
  • follicular lymphoma grade 3
  • HIV-associated atypical follicular hyperplasia
  • blastic mantle zone lymphoma
  • transformed marginal zone lymphoma

• diffuse large B-cell lymphomas
  • diffuse large B-cell lymphoma (DLBCL)
  • Burkitt lymphoma (middle size B-cell lymphoma)