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metanephric adenofibroma
Monday 27 October 2003
Microscopical synopsis
intratumoral angiodysplasia
concentric cuffing of entrapped tubules ("onion skinning")
heterologous differentiation
epithelial components
- inactive embryonal epithelium (identical morphologically to metanephric adenoma (MA)
- carcinomatous component distinct from these lesions but identical morphologically to papillary renal cell carcinoma (PRCC).
Prognosis
metastases to the regional lymph nodes at the time of diagnosis (1/9) (11257617)
Differential diagnosis
congenital mesoblastic nephroma (CMN) -> intratumoral angiodysplasia, concentric cuffing of entrapped tubules ("onion skinning"), and heterologous differentiation. (11257617)
See also
Tumors
- renal tumors
metanephric adenoma
References
Arroyo MR, Green DM, Perlman EJ, Beckwith JB, Argani P. The spectrum of metanephric adenofibroma and related lesions: clinicopathologic study of 25 cases from the National Wilms Tumor Study Group Pathology Center. Am J Surg Pathol. 2001 Apr;25(4):433-44. PMID: 11257617
