Home > E. Pathology by systems > Nervous system > Central nervous system > ALS-FTD
ALS-FTD
Sunday 20 April 2008
About 5% of ALS patients have a progressive dementia with executive dysfunction, personality change, and motor weakness. The disease course is more rapid than patients with either FTD or ALS alone.
Etiology
TARDBP (TDP-43) germline mutations