monocarboxylate transporters
MCTs
Monocarboxylate transporters (MCTs) typically have 12 transmembrane domains, intracellular N and C termini, and a large intracellular loop between transmembrane domains 6 and 7.
Examples
SLC5A2 (ex-SLC16A12)
Pathology
germline mutation in the sodium/glucose cotransporter SGLT2 encoded by the SLC5A2 gene (MIM.182381) in autosomal recessive renal glucosuria (MIM.233100)
See also
SLCs
- SLC5s