Home > D. General pathology > Genetic and developmental anomalies > Genetic metabolic diseases > maternal diabetes
maternal diabetes
Tuesday 4 March 2008
Synopsis
diabetic embryopathy with fetal malformations
-
caudal dysplasia (caudal regression syndrome) (15266776, 15127755, 14694401, 12196475. 11896527, 7365764, 4848209)
- sirenomelia (15266776)
- severe axial mesodermal dysplasia spectrum (8775416)
- lumbosacral dysgenesis (457742)
- VACTERL association (118181216)
- femoral hypoplasia i(18051935, 8960613, 8330451)
- femoral hypoplasia-unusual facies syndrome (FHUFS) (17668891, 8960613, 6854450)
- bifid tongue (17663469)
- holoprosencephaly (17274816, 8330451)
- congenital cryptorchidism (17032715)
- extrahepatic biliary atresia (14694401)
- penile enlargement (11170094)
- oculoauriculovertebral anomalies (10710228)
- limb reduction defects (9018422)
- cardiovascular malformations (9018422)
- renal agenesis (9018422)
- branchial arch malformations (6753584)
- central nervous system malformations (6753584)
- vertebral malformations (6753584)
- central nervous system malformations (6753584)
- bilateral renal agenesis (6891697)
- Di George syndrome (6891697)
References
Kapoor N, Sankaran S, Hyer S, Shehata H. Diabetes in pregnancy: a review of current evidence. Curr Opin Obstet Gynecol. 2007 Dec;19(6):586-90. PMID: 18007138
Allen VM, Armson BA, Wilson RD, Allen VM, Blight C, Gagnon A, Johnson JA, Langlois S, Summers A, Wyatt P, Farine D, Armson BA, Crane J, Delisle MF, Keenan-Lindsay L, Morin V, Schneider CE, Van Aerde J, Society of Obstetricians and Gynecologists of Canada.Teratogenicity associated with pre-existing and gestational diabetes. J Obstet Gynaecol Can. 2007 Nov;29(11):927-44. PMID: 17977497
Barnes-Powell LL.Infants of diabetic mothers: the effects of hyperglycemia on the fetus and neonate.Neonatal Netw. 2007 Sep-Oct;26(5):283-90. PMID: 17926658
Madri JA, Enciso J, Pinter E. Maternal diabetes: effects on embryonic vascular development—a vascular endothelial growth factor-A-mediated process. Pediatr Dev Pathol. 2003 Jul-Aug;6(4):334-41. PMID: 14692647
