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HEYs
Monday 14 January 2008
Definition: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix transcription factors (bHLH transcription factors) implicated in cell fate decision and boundary formation.
HEYs genes are direct transcriptional targets of the Notch signaling pathway in Drosophila and vertebrates.
Members
| HEY1 | HEY2 |
Pathology
Pathology
HEY1-NCOA2 Gene Fusion in mesenchymal chondrosarcoma (27544802)
- between HEY1 and NCOA2
Open references
Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma. Panagopoulos I, Gorunova L, Bjerkehagen B, Boye K, Heim S.
Oncol Rep. 2014 Jul;32(1):40-4. doi : 10.3892/or.2014.3180
PMID: 24839999
See also
HEYL
Notch signaling pathway
