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undifferentiated small round cell sarcoma

Cytogenetics

- isolated trisomy 8 (trisomy 8-associated undifferentiated sarcoma)(#17350464#)

- EWSR1/SP3 fusion gene (#17690209#)

References

- Selvarajah S, Yoshimoto M, Prasad M, Shago M, Squire JA, Zielenska M, Somers GR.Characterization of trisomy 8 in pediatric undifferentiated sarcomas using advanced molecular cytogenetic techniques.Cancer Genet Cytogenet. 2007 Apr 1;174(1):35-41. PMID: #17350464#

- G.R. Somers, A.A. Gupta, A.S. Doria, M. Ho, C. Pereira, M. Shago, P.S. Thorner and M. Zielenska, Pediatric undifferentiated sarcoma of the soft tissues: a clinicopathologic study, Pediatr Dev Pathol 9 (2006), pp. 132–142.

- Wang L, Bhargava R, Zheng T, Wexler L, Collins MH, Roulston D, Ladanyi M. Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions. J Mol Diagn. 2007 Sep;9(4):498-509. PMID: #17690209#