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zymogen granules

Monday 19 June 2017

PAS positive zymogen granules

Definition: Basophilic granular cytoplasm filled with PAS positive (diastase resistant) zymogen granules can be observed in acinic cell carcinoma is an encapsulated carcinoma that shows cells with

It is positive for amylase, and has a prominent lymphocytic infiltrate. It is most common in the parotid and minor salivary glands.

On cytology, it shows oncocytic type cells with zymogen granules, many stripped nuclei due to cell fragility, lymphocytes, and benign epithelial cells.