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zymogen granules
Monday 19 June 2017
PAS positive zymogen granules
Definition: Basophilic granular cytoplasm filled with PAS positive (diastase resistant) zymogen granules can be observed in acinic cell carcinoma is an encapsulated carcinoma that shows cells with
It is positive for amylase, and has a prominent lymphocytic infiltrate. It is most common in the parotid and minor salivary glands.
On cytology, it shows oncocytic type cells with zymogen granules, many stripped nuclei due to cell fragility, lymphocytes, and benign epithelial cells.