pregnancy-associated stroke (PAS)

Pregnancy, cesarean delivery and the post- partum period are associated with an increased risk of cerebrovascular events.

Factors that may contribute to ischemic strokes during gestation and puerperium include classic cardiovascular risk factors, changes in hemostaseology/hemodynamics, and pregnancy-specific disorders such as pre-eclampsia, eclampsia, post-partum cerebral angiopathy or peripartum cardiomyopathy.

Older age is associated with increased risk of pregnancy-associated stroke (PAS).

Younger women, but not older women, have an increased stroke risk during pregnancy and post-partum compared with their non-pregnant contemporaries. Some results suggest that pregnancy does not increase the risk of stroke in older women. (27775757)

Etiology

 post-partum angiopathy

• Post-Partum Angiopathy presenting as Ischemic Stroke.

Paywall references

 Risk of Pregnancy-Associated Stroke Across Age Groups in New York State.
Miller EC, Gatollari HJ, Too G, Boehme AK, Leffert L, Elkind MS, Willey JZ.
JAMA Neurol. 2016 Oct 24. doi : 10.1001/jamaneurol.2016.3774 PMID: 27775757

 Cryptogenic postpartum stroke. Bereczki D Jr, Szegedi N, Szakács Z, Gubucz I, May Z. Neurol Neurochir Pol. 2016;50(5):370-3. doi : 10.1016/j.pjnns.2016.05.001
PMID: 27591063